CRISPR-Cas9, an acronym for “Clustered regularly-interspaced short palindromic repeats.”
VSF: This is ET/alien technology given like a Trojan Horse to implement the Alien Invasion.
What is stopping CRISPR technology from being weaponized, eliminating any people not having chosen genetic markers?
https://www.youtube.com/watch?v=jAhjPd4uNFY is well produced, accessible, and intelligent view of the technology. It also acknowledges dark possibilities that I’d like to seek council on.
1.) Some international conglomerates act unethically.2.) Some governments have issues with systemic corruption, or poor oversight.3.) Some talented individual scientists can be unbalanced or leveraged.
4.) CRISPR tech is relatively: new, powerful, easy to implement, and low barrier.
5.) Lab equipment and technical knowledge are easy to come about on the web.
6.) Some people see overpopulation as the prime threat to humanity.
7.) Lab trained scientists are undergoing a boom in numbers.
8.) Some people hold bigotry as a core motivation.
9.) The idea is a real, nurtured, and propagated narrative.
10.) Some people want to watch the world burn. (This would allow them to watch).
11.) Figuring things out is what scientists do. Current barriers can be overcome, whether it’s how to weaponize a virus, a bacteria, a food/water/air/item source, or to develop another delivery system.
12.) Humans can be scarred, self interested, detached, egomaniacs.
13.) We haven’t developed a technology yet we have not weaponized.
14.) The stakes are absolute.
The factors above aren’t a systematic or exhaustive. I don’t think this should be dismissed. A think-tank, or a government council, or a international coalition, or a broad public effort to develop awareness wouldn’t be amiss. I’m a upbeat, mature, worldly person with degrees in biology and ethics. This is not scare mongering or based in emotional terror. It’s a valid vision at the outset of a world changing technology that has an opportunity to be addressed. What can be done?
CRISPR-Cas9, an acronym for “Clustered regularly-interspaced short palindromic repeats.”
Statement for the Record Worldwide Threat Assessment of the US Intelligence Community Senate Armed Services Committee
9 Genome Editing Research in genome editing conducted by countries with different regulatory or ethical standards than those of Western countries probably increases the risk of the creation of potentially harmful biological agents or products. Given the broad distribution, low cost, and accelerated pace of development of this dual-use technology, its deliberate or unintentional misuse might lead to far-reaching economic and national security implications.
Advances in genome editing in 2015 have compelled groups of high-profile US and European biologists to question unregulated editing of the human germline(cells that are relevant for reproduction), which might create inheritable genetic changes. Nevertheless, researchers will probably continue to encounter challenges to achieve the desired outcome of their genome modifications, in part because of the technical limitations that are inherent in available genome editing systems
As Made-To-Order DNA Gets Cheaper, Keeping It Out Of The Wrong Hands Gets Harder
September 24, 2019
“Today, we are synthesizing more than 10,000 genes every month,” he says, showing off a lab at a Boston biotech company called Ginkgo Bioworks.
Making genes from scratch used to be laborious and time consuming, but not anymore. That’s why federal officials are now considering new measures to prevent this rapidly advancing technology from being misused to create dangerous viruses or bioweapons.
… the global synthetic DNA industry is currently churning out approximately 3 billion pairs of DNA letters a year—or about the same amount found in each human cell.
She says her company produces about 10 percent of that, and its customers include pharmaceutical firms, agricultural companies and academic scientists trying to understand basic biology.
“You log on to the website, you upload the sequence you want and you can order one gene or 10 genes or a thousand genes,” explains Leproust.
A couple weeks later, custom DNA arrives in the mail. At least, it does if the order gets through Twist Bioscience’s rigorous security screening.
What makes DNA so powerful, after all, also makes it potentially dangerous. Someone could use it to change a harmless bacteria into one that makes a deadly toxin.
And scientists have already shown that it’s possible to use bits of DNA to construct viruses like polio and Ebola.
Bill Gates And 13 Other Investors Pour $120 Million Into Revolutionary Gene-Editing Startup
Four years ago, the protein called CRISPR-Cas9, an enzyme that bacteria use to attack viruses that infect them, was unknown to humans.
Now it is ubiquitous in science labs as the most efficient way of cutting-and-pasting DNA yet invented. Wired Magazine, in a breathless cover story, just called it “The Genesis Engine,” instructing readers to “buckle up” because the easy DNA editing CRISPR enables will change the world. And now at least one CRISPR-focused company has the cash to back up the hype.
Editas Medicine, based in Cambridge, Mass., already had money. Founded in November 2013 with $43 million from Third Rock Ventures, Polaris Ventures and Flagship Ventures, it was the first big CRISPR effort out of the gate. The company says that money has not been spent. In May, Juno Therapeutics, which is developing cell therapies for cancer, inked a collaboration that gave Editas $25 million upfront and another $22 million in research support. Any products that result could deliver Editas another $250 million.
But those investments are dwarfed by today’s announcement, which will put $120 million into the tiny company’s bank account – enough, Editas says, to keep it running for a projected three years. The lead investor is a newly created firm called bng0, a select group of family offices led by Boris Nikolic, who was previously a science advisor to Bill Gates. Both Editas and Gates’ office confirm that the Microsoft billionaire, who is the world’s richest man, is among the bng0 backers.
• Bill Gates is advocating for the use of genetic editing tools like CRISPR. • CRISPR allows scientists to edit DNA, eliminating undesirable genes and potentially swapping in preferable alternatives. • Gates thinks we could use genetic editing to make livestock and crops more sustainable and to eliminate malaria-causing mosquitoes.
Gates has long been supportive of using genetic editing tools. He was one of the early investors in Editas Medicine, one of the first companies to start trying to use CRISPR to eliminate human diseases. Gates Foundation researchers have worked for nearly a decade on ways to use genetic editing to improve crops and to wipe out malaria-carrying mosquitoes.
Gates Foundation awards $12 million to teams hunting for universal flu vaccine
Helen Branswell | STAT | September 10, 2019
Scientific teams from inside and outside the world of influenza research have been awarded funding to try to unlock mysteries that could provide the foundation for a future universal flu vaccine, the Bill and Melinda Gates Foundation and the philanthropy Flu Lab have announced.
The funds, up to $12 million, will be awarded to as many as eight teams of researchers, the Gates Foundation and Flu Lab announced [August 29] at Options for the Control of Influenza, the flu world’s largest scientific conference.
The foundation and Flu Lab recognized that on the issue of universal flu vaccines, there were two camps. One is pursuing incremental ways to make flu vaccines more broadly protective, but does not aim for what is often referred to as the holy grail of influenza — a vaccine that could protect against all flu viruses.
Is Gene Editing the New Name for Eugenics?
A major new technology known as Gene Editing has gained significant attention in recent months. Its advocates claim it will revolutionize everything from agriculture production to disease treatment. None other than Bill Gates has just come out in an article in the US foreign policy magazine Foreign Affairs in praise of the promise of gene editing. Yet a closer investigation suggests that all is not so ideal with Gene Editing. New peer reviewed studies suggest it could cause cancer. The question is whether this technology, which is highly controversial, is little more than a stealth way to introduce GMO genetic manipulation by way of another technique.
The scientific magazine, Nature Studies, has published two studies that suggest that gene-editing techniques may weaken a person’s ability to fight off tumors, and “could give rise to cancer, raising concerns about for the safety of CRISPR-based gene therapies.” The studies were done by Sweden’s Karolinska Institute and by the pharmaceutical firm, Novartis. Cells whose genomes are successfully edited by CRISPR-Cas9 have the potential to seed tumors inside a patient the studies found. That could make some CRISPR’d cells ticking time bombs, according to researchers from Karolinska Institute and, in a separate study, by Novartis.
The CEO of CRISPR Therapeutics, Sam Kulkarni, admitted that the results are “plausible.” He added,
“it’s something we need to pay attention to, especially as CRISPR expands to more diseases.”
Given the stakes that is a notably nonchalant response.
Genes out of the bottle
The issue of gene editing to cut or modify DNA of a plant, animal or potentially human beings is by no means mature let alone fully tested or proven safe as the two new studies suggest. CRISPR, far the most cited gene editing technology, was developed only in 2013. In 2015 at a London TED conference geneticist Jennifer Doudna presented what is known as CRISPR-Cas9, an acronym for “Clustered regularly-interspaced short palindromic repeats.” It’s a gene-editing platform using a bacterially-derived protein, Cas9 that supposedly allows genetic engineers to target and break the DNA double strand at a precise location within a given genome for the first time.